The most common symptoms of Waldenstrom macroglobulinemia (WM)

The most common symptoms of Waldenstrom macroglobulinemia (WM) are:

Weakness

The most common symptom of WM is weakness. It can be caused by anemia (low red blood cells) which can happen when the lymphoma cells crowd out normal cells in the bone marrow. Some people also feel weak when the blood becomes thick from the abnormal protein.

Loss of appetite

About one-fourth of patients lose their appetite.

Fever

Lymphoma can cause fevers (without an infection), drenchin g night sweats, and weight
loss. Together, these 3 symptoms are called B-symptoms
.

Neuropathy

 The abnormal antibody in some people with WM can attack and damage nerves outside
the brain. This can lead to problems with numbness or a painful "pins and needles"
sensation in the feet and legs, which is called neuropathy